{"id":233536,"date":"2026-02-05T09:09:44","date_gmt":"2026-02-05T08:09:44","guid":{"rendered":"https:\/\/www.alimentibevande.it\/sponsored-contents\/cereulide-nei-lattanti-efsa-stabilisce-la-dose-acuta-di-riferimento\/"},"modified":"2026-02-05T09:54:55","modified_gmt":"2026-02-05T08:54:55","slug":"cereulide-in-infants-efsa-establishes-acute-reference-dose","status":"publish","type":"post","link":"https:\/\/www.alimentibevande.it\/en\/food-safety\/cereulide-in-infants-efsa-establishes-acute-reference-dose\/","title":{"rendered":"Cereulide in infants: Efsa establishes acute reference dose"},"content":{"rendered":"\n

The acute reference dose (DAR) <\/strong>for cereulide <\/strong>toxin in infants <\/strong>is 0.014 \u03bcg\/kg<\/strong> body weight, as proposed by scientists at the European Food Safety Authority (EFSA) <\/strong>in their opinion<\/a> <\/strong>published on 2 February.<\/p>\n\n\n\n

\"\"<\/a>
\u00a9<\/sup> Lucio Rossi for Efsa, Studio Valle Progettazioni, Art & Build, Manens -Tifs, Pool Engineering, Art Ambiente Risorse and Territorio<\/em><\/kbd><\/figcaption><\/figure>\n\n\n\n

The document was drafted following a request from the European Commission<\/a><\/strong> for urgent scientific advice in light of recalls<\/a> <\/strong>of various baby foods<\/strong> in several countries due to the discovery of a toxin produced by the bacterium Bacillus cereus<\/strong>. EFSA’s opinion will be used to support risk management decisions to be taken across the European Union.<\/p>\n\n\n\n

To establish the DAR, EFSA scientists used reference dose modelling and considered emesis <\/strong>(vomiting) as the most relevant acute adverse effect.<\/p>\n\n\n\n

The value per kilogram of body weight for estimating short-term exposure (24 hours<\/strong>) was 260 ml<\/strong> for infant formula and 140 ml<\/strong> for follow-on formula, based \u2013 according to EFSA in a note \u2013 on the \u201cmaximum amount that infants usually drink, so that the assessment remains precautionary\u201d.<\/p>\n\n\n\n

Scientists at the European Food Safety Authority then compared DAR with these consumption values, concluding that “cereulide concentrations in reconstituted infant formula (liquid) above 0.054 \u03bcg\/L<\/strong> and 0.1 \u03bcg\/L<\/strong> in follow-on formula may lead to safety levels being exceeded”.<\/p>\n\n\n\n

For infants who develop vomiting or diarrhoea after consuming infant formula affected by the current recalls, the European Centre for Disease Prevention and Control (ECDC) <\/a><\/strong>recommends consulting a paediatrician or other similar healthcare professionals and, in case of severe symptoms such as dehydration or persistent vomiting, seeking emergency medical attention.<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

The toxin, produced by the bacterium Bacillus cereus, has been found in various baby foods in several European countries<\/p>\n","protected":false},"author":3836,"featured_media":233537,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[20576],"tags":[20709,20688,20712,20694],"tipologia":[],"coauthors":[20589],"class_list":["post-233536","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-food-safety","tag-cereulide","tag-food-safety","tag-infants","tag-lattanti"],"acf":[],"yoast_head":"\nCereulide in infants: Efsa establishes acute reference dose - Alimentibevande.it<\/title>\n<meta name=\"description\" content=\"The toxin, produced by the bacterium Bacillus cereus, has been found in various baby foods in several European countries\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, 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